NIH RPPR Instruction Guide

1 Purpose ...................................................................................................................................................13 1.1 NIH ....................................................................................................................................................13 1.2 Agency for Healthcare Research and Quality (AHRQ) .....................................................................13 1.3 Department of Veterans Affairs (VA) ...............................................................................................13 2 Background and Paperwork Burden ...................................................................................................13 3 RPPR Due Dates.....................................................................................................................................14 3.1 NIH ....................................................................................................................................................14 3.2 Agency for Healthcare Research and Quality (AHRQ) .....................................................................15 4 Data Entry, PDF Attachments, and Style.............................................................................................15 4.1 Data or Text Box, and PDF Size Limits ............................................................................................15 4.2 PDF Attachments ...............................................................................................................................15 4.3 Style ...................................................................................................................................................16 5 Navigation ...............................................................................................................................................16 5.1 Initiate the RPPR ...............................................................................................................................17 5.2 Accessing the RPPR From Closeout .................................................................................................23 5.2.1 Starting Your Final Research Performance Progress Report .........................................................25 5.3 Edit the RPPR ....................................................................................................................................26 5.3.1 Access RPPR From Status ............................................................................................................26 5.3.2 Access RPPR From the RPPR Module in eRA Commons ............................................................29 5.3.3 Accessing a Single-Project RPPR for Editing ...............................................................................29 5.3.4 Accessing a Multi-Project and Single-Project with Complicated Structure RPPR for Editing ....30 5.3.5 Editing the RPPR Forms ...............................................................................................................33 5.3.6 Editing Inclusion Enrollment Data .................................................................................................37 5.3.7 Editing the RPPR Budget Forms ...................................................................................................42 5.4 Check RPPR for Errors and Warnings ..............................................................................................47 5.4.1 Checking for Errors on Single-Project RPPRs ...............................................................................47 5.4.2 Checking for Errors on a Multi-Project RPPR ..............................................................................47 5.5 Route the RPPR .................................................................................................................................48 5.6 Recall the RPPR ................................................................................................................................50 5.7 Submit the RPPR to Agency..............................................................................................................51 5.7.1 Submission Errors and Warnings for Multi-Project RPPRs ..........................................................53 NIH RPPR Instruction Guide 8 January 2026 5.8 View the RPPR ..................................................................................................................................54 5.9 View Routing History ........................................................................................................................54 5.10 Viewing the Completed RPPR in Commons .....................................................................................55 5.11 Public Access Progress Report Additional Materials (PRAM) .........................................................58 5.11.1 Initiate Public Access PRAM ........................................................................................................59 5.11.2 Recall Public Access PRAM .........................................................................................................61 5.11.3 Submit Public Access PRAM ........................................................................................................62 5.11.4 View Public Access PRAM for Multi-Year Funded Awards ........................................................65 5.12 Final Progress Report Additional Materials (FRAM)........................................................................67 5.12.1 Uploading Final Report Additional Materials ...............................................................................69 5.12.2 Submitting FRAM .........................................................................................................................72 5.13 Interim Report Additional Materials (IRAM)....................................................................................73 5.14 Agency Requested Progress Report Additional Materials (PRAM) ..................................................77 5.14.1 Initiate Agency Requested PRAM .................................................................................................78 5.14.2 Recall Agency Requested PRAM ..................................................................................................81 5.14.3 Submit Agency Requested PRAM .................................................................................................82 5.14.4 View Agency Requested PRAM from Status Information .............................................................85 6 Instructions for RPPR Sections A–I .....................................................................................................87 6.1 Section A – Cover Page .....................................................................................................................87 6.2 Section B – Accomplishments ...........................................................................................................89 6.3 Section C – Products..........................................................................................................................94 6.4 Section D – Participants...................................................................................................................103 6.5 Section E – Impact ...........................................................................................................................111 6.6 Section F – Changes ........................................................................................................................113 6.7 Section G – Special Reporting Requirements ..................................................................................116 6.8 Section H – Budget [Applicable to non-SNAP awards only] ..........................................................131 6.9 Section I – Outcomes .......................................................................................................................134 7 Supplemental Instructions for Specific Grant RPPR Types .............................................................136 7.1 Individual Career Development (K) RPPRs ....................................................................................136 7.2 Fellowship RPPRs ...........................................................................................................................139 7.3 SBIR/STTR RPPRs .........................................................................................................................142 7.4 Training RPPRs ...............................................................................................................................146 7.5 Education RPPRs.............................................................................................................................150 7.6 Multi-Project RPPRs and Single-Project RPPRs with Complicated Structure ................................152 NIH RPPR Instruction Guide 9 January 2026 7.6.1 Overall .........................................................................................................................................152 7.6.2 Component Instructions ..............................................................................................................155 8 Assurances/Certifications ....................................................................................................................159 9 Government Use of Information Under the Privacy Act ..................................................................160 NIH RPPR Instruction Guide January 2026 10 Table of Figures Figure 1 Figure 1 RPPR Navigation Links from Cover Page 17 Figure 2 Status Screen for PIs, showing List of Applications/Awards 18 Figure 3 RPPR Button on Status Result – List of Applications/Awards 19 Figure 4 Multi-Year Award RPPR Link 19 Figure 5 Manage RPPR List of Applications/Awards 20 Figure 6 RPPR Menu for Initiating the Report 22 Figure 7 Requires Closeout Button 24 Figure 8 Closeout Status Screen 24 Figure 9 Final RPPR Menu 25 Figure 10 PI view of Status Screen, showing List of Applications/Awards heading 27 Figure 11 RPPR Button on PI’s Status Result – List of Applications/Awards screen 28 Figure 12 Multi-Year Funded Award RPPR Button 28 Figure 13 Manage RPPR List of Applications/Awards 29 Figure 14 SO view of RPPR actions under the three-dot ellipsis menu (including Submit action, available to SOs only) 30 Figure 15 RPPR Menu Options for Multi-Project RPPRs 31 Figure 16 Edit Option for Overall 32 Figure 17 Add New Component Popup 33 Figure 18 RPPR Cover Page and Section Navigation Links 34 Figure 19Add Button and Edit and Delete actions available from the three-dot ellipsis menu in a table 35 Figure 20Total Remaining Characters 35 Figure 21Standard Table Tools 36 Figure 22Filter Table Field 36 Figure 23Column Sort Options 36 Figure 24 Download Tool 36 Figure 25 Rows-per-Page Tool 36 Figure 26 Navigation Tools 37 Figure 27 Human Subjects Link in Question G.4 37 Figure 28 Manage IERs for Single Project 38 Figure 29 Adding/Editing an Inclusion Enrollment Report 39 Figure 30 Inclusion Enrollment Report Fields 40 Figure 31 Cumulative (Actual) Enrollment Table 41 Figure 32 RPPR H. Budget - Questions H.1 Budget Form & H.2 Subaward Budget Form 44 Figure 33 Organizational UEI on SF 424 Research & Related Budget 45 Figure 34 Search Organization popup window 45 Figure 35 SF 424 R&R Budget Form - Question F.5 46 Figure 36 Check for Errors option on RPPR Menu for a Single-Project RPPR 47 Figure 37 RPPR Error Messages (Examples) 47 Figure 38 Check for Errors Link for Multi-Project RPPRs 48 Figure 39 Errors and Warnings for One Component of a Multi-Project RPPR 48 Figure 40 RPPR Menu – Route Option 49 Figure 41 Route RPPR to Next Reviewer 49 Figure 42 Route RPPR to Next Reviewer Success Message 50 Figure 43 RPPR Menu – Recall Option 50 Figure 44 RPPR Successfully Recalled 51 Figure 45 Submit Option on RPPR Menu 51 Figure 46 Successful Submission Message 53 Figure 47 Sample of Multi-Project RPPR Error Messages 53 Figure 48 RPPR Menu – View the RPPR Option 54 Figure 49 RPPR Menu – View Routing History Option 54 Figure 50 RPPR Routing History 55 Figure 51 PI view of Status, showing the List of Applications/Awards 55 NIH RPPR Instruction Guide January 2026 11 Figure 52 Application/Award ID link 56 Figure 53 Status Information Screen – e-Application Link 57 Figure 54 Status Information Screen for Multi-Year RPPR 58 Figure 55 Public Access PRAM Link 59 Figure 56 Routing the Public Access PRAM 60 Figure 57 Route Public Access PRAM to Next Reviewer 60 Figure 58 Public Access PRAM PD/PI Assurance Statement 61 Figure 59 Recall Button for Public Access PRAM 62 Figure 60 Public Access PRAM Link for SO 63 Figure 61 Submitting Public Access PRAM 63 Figure 62 SO Certification of Public Access PRAM 64 Figure 63 Public Access PRAM Submitted to Agency 65 Figure 64 Status Results Showing link for Application/Award ID 66 Figure 65 MYF Award PRAM Link in Status Information 66 Figure 66 Final Progress Report Additional Materials 68 Figure 67 Closeout Status showing FRAM Update 70 Figure 68 Closeout Final Report Additional Materials Request in Status Information 71 Figure 69 Closeout Status FRAM Uploaded message in Status column 71 Figure 70 Closeout Status with FRAM Update button in Action column 72 Figure 71 Final Progress Report Additional Materials showing the Submit button 73 Figure 72 Interim Progress Report Additional Materials 74 Figure 73 IRAM action as seen in Status by a signing official (SO) 75 Figure 74 IRAM action as seen in Status by a principal investigator (PI) 75 Figure 75 Interim Progress Report Additional Materials 77 Figure 76 Agency Requested PRAM button 78 Figure 77 Agency Requested PRAM screen 79 Figure 78 Routing the Agency Requested PRAM 79 Figure 79 Route Agency Requested PRAM to Next Reviewer 80 Figure 80 Agency Requested PRAM PD/PI Assurance Statement 80 Figure 81 Successfully Routed Agency Requested PRAM 81 Figure 82 Recall Button for Agency Requested PRAM 81 Figure 83 Agency Requested PRAM Link for SO 82 Figure 84 Submitting Agency Requested PRAM 83 Figure 85 SO Certification of PRAM 84 Figure 86 Agency Requested PRAM Submitted to Agency 84 Figure 87 Application/Award ID link on Status Result for PIs 85 Figure 88 Application/Award ID link on Status Result for SOs 85 Figure 89 Status Information with PRAM Link 86 Figure 90 PDF of Multiple Submitted PRAM 86 Figure 91 Section A, cover page 88 Figure 92 RPPR Section B. Accomplishments – Question B1 89 Figure 93 RPPR Section B. Accomplishments – Questions B2 & B3 91 Figure 94 RPPR Section B. Accomplishments – Question B4 92 Figure 95 RPPR Section B. Accomplishments – Question B5 93 Figure 96 RPPR Section B. Accomplishments – Question B6 93 Figure 97 RPPR Section C. Products – Question C1 96 Figure 98 RPPR Section C. Products – Questions C2 & C3 98 Figure 99 RPPR Section C. Products – Questions C4 & C5.a and C5.b 100 Figure 100 RPPR Section C.5.c Data Management and Sharing 102 Figure 101 RPPR Section D. Participants – Question D1 103 Figure 102 Senior/Key Personnel section of D.1 106 Figure 103 Upload areas for adding a new Senior/Key Personnel 107 Figure 104 Upload areas for changes in current or pending other support 108 Figure 105 New Other Significant Contributor upload area 109 Figure 106 Is the individual affiliated with a foreign organization question 110 NIH RPPR Instruction Guide January 2026 12 Figure 107 D.2.a Level of Effort section 110 Figure 108 D.2.e Multi-PI (MPI) Leadership Plan section 111 Figure 109 RPPR Section E. Impact – Questions E1 through E4 113 Figure 110 RPPR Section F. Changes – Questions F1 & F2 114 Figure 111 RPPR Section F Changes- Question F3 115 Figure 112 RPPR Section G.1. SBIR/STTR Foreign Disclosure Form question appear for SBIR/STTR awards only. 118 Figure 113 RPPR Section G. Special Reporting Requirements – Questions G1 through G3 119 Figure 114 Human Subjects Link 119 Figure 115 HSCT Post Submission tab in ASSIST (for Human Subjects) 120 Figure 116 Question G.4 for AHRQ Recipients Only 121 Figure 117 Section 1: Basic Information of HSCT Tab in ASSIST with Populate Button 123 Figure 118 Clinical Trial Milestone Plan, which is on the HSCT form in the Human Subjects System (HSS) 124 Figure 119 RPPR Section G. Special Reporting Requirements – Question G.4 126 Figure 120 RPPR Section G. Special Reporting Requirements – Questions G5 through G7 127 Figure 121 RPPR Section G. Special Reporting Requirements – Question G8 128 Figure 122 RPPR Section G. Special Reporting Requirements – Question G9 129 Figure 123 RPPR Section G. Special Reporting Requirements – Questions G10 through G12 131 Figure 124 Section H. Budget of RPPR for a Non-SNAP Award 132 Figure 125 SF 424 Research & Related Budget Form Opened for Editing 133 Figure 126 SF 424 R&R Budget Form - Question F.5 134 Figure 127 Section I. Outcomes 135 Figure 128 SF 424 R&R Budget Form - Question F.5 139 Figure 129 Question C.5.c Data Management and Sharing 143 Figure 130 RPPR Section G.1. SBIR/STTR Foreign Disclosure Form question appears for SBIR/STTR awards only. 145 Figure 131 SF 424 R&R Budget Form - Question F.5 150 Figure 132 D.1 Specifying the Components for an Added Individual 153 Figure 133 SF 424 R&R Budget Form - Question F.5 155 Figure 134 Sample of Section A. Cover Page for a Component 156 Figure 135 SF 424 R&R Budget Form - Question F.5 159 NIH RPPR Instruction Guide 13 January 2026 1 Purpose The purpose of this document is to provide those preparing the Research Performance Progress Report (RPPR) with an explanation of the RPPR module in the eRA Commons and the information required in the report. This document also provides the steps for accessing and completing the report in eRA Commons, as well as navigating, validating, routing, and submitting the RPPR to the awarding agency. 1.1 NIH The RPPR is required for all annual non-competing (Type 5) NIH awards and final progress reports (Final-RPPR), including SBIR/STTR awards. NIH requires the submission of an “Interim-RPPR” if the recipient organization has submitted a renewal application (Type 2) on or before the due date by which a Final-RPPR would be required for the current competitive segment. Annual, interim, and final progress reports submitted in any format other than the RPPR will not be processed by the NIH and will require resubmission through the RPPR. Refer to notices NOT-OD-17-022, NOT-OD-17-037, NOT-OD-17- 085, NOT-OD-13-035, NOT-OD-14-026 and NOT-OD-14-092 and NOT-OD-15-014 for more information. 1.2 Agency for Healthcare Research and Quality (AHRQ) All Agency for Healthcare Research and Quality (AHRQ) recipients are required to use the eRA Commons RPPR module. The RPPR includes numerous references to the NIH Grants Policy Statement 8.1.2 requirement that significant changes in objectives and scope require prior approval of the agency; for AHRQ recipients the analogous requirement is in the HHS Grants Policy Statement under “Prior Approvals.” AHRQ recipients also use the eRA Commons Closeout procedures and screens. AHRQ will complete the Final Research Performance Progress Report (FRPPR) closeout action, accessible from the Status module under the Requires Closeout action. 1.3 Department of Veterans Affairs (VA) Progress reports (RPPRs) are required to continue support of a VA-ORD award for each budget year within a competitive segment. Interim reports are due when the project period is over and the award is not in Closeout (i.e., a renewal application is pending or has been selected for funding). If the pending renewal application is not funded, the Interim report becomes the Final report. Final reports are required for any funded award that has ended and will not be extended through renewal. Note: For VA awards the outcomes are not published. Guidance on completing report content specific to VA-ORD requirements, as well as navigating, validating, routing and submitting the report to VA-ORD for review and approval can be found at: https://www.research.va.gov/resources/RPPR.cfm. It is important to review the VA- ORD instructions as there are sections where specific VA-ORD information is requested that differs from that noted within the NIH progress report template: https://grants.nih.gov/grants/guide/notice-files/NOT-OD-17-022.html https://grants.nih.gov/grants/guide/notice-files/NOT-OD-17-037.html 2 Background and Paperwork Burden The NIH Research Performance Progress Report (RPPR) implements the uniform reporting format for interim research progress reporting developed under the auspices of the National Science and Technology Council, through the Committee on Science and the Research Business Models Subcommittee, and established by the Office of Management and Budget for use by agencies that support research and research-related activities. NIH RPPR Instruction Guide 14 January 2026 For NIH and AHRQ, all progress reports must be submitted using the RPPR. Other PHS agencies that may eventually utilize the NIH RPPR are the Food and Drug Administration, and Centers for Disease Control and Prevention. Non-NIH agencies may have requirements that differ from those for NIH recipients; refer to the Notice of Award (NoA) or contact the Grants Management Specialist named in the NoA. Progress reports are required to continue support of a PHS grant for each budget year within a competitive segment. NIH has implemented the Final and Interim-RPPR for final progress reporting at the end of each competitive segment. AHRQ award recipients can find instructions for submitting the Final Progress Report or Final Research Performance Progress Report in online help; see Closeout for AHRQ Awards. Also see Grant Closeout Requirements on the AHRQ website. Public reporting burden for this collection of information is estimated to 15 hours per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. An agency may not conduct or sponsor, and a person is not required to respond to, a collection of information unless it displays a currently valid OMB control number. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to: NIH, Project Clearance Office, 6705 Rockledge Drive MSC 7974, Bethesda, MD 20892-7974, ATTN: PRA (0925-0002). Do not send progress reports to this address. 3 RPPR Due Dates Signing officials of recipient organizations can find progress reports that are due by following the steps in How to Find Annual Awards with Progress Reports Due? in the online help topic: Finding Recent NoAs, Awards with RPPRs Due, or Awards Pending Closeout. In addition, automatic e-mail notifications are sent to the PD/PI prior to due date. 3.1 NIH • SNAP: If an award is issued under the SNAP (Streamlined Noncompeting Award Process) provisions, the progress report is due the 15th of the month preceding the month in which the budget period ends (e.g., if the budget period ends 11/30, the due date is 10/15). If the 15th falls on a weekend or Federal holiday, the due date is automatically extended to the next business day. Recipients should consult the NoA to determine when SNAP procedures apply. • Non-SNAP: If an award is not issued under the SNAP provisions, the progress report is due the first of the month preceding the month in which the budget period ends (e.g., if the budget period ends 11/30, the due date is 10/1). • Fellowships: For Fellowships, the progress report is due two months before the beginning date of the next budget period. Occasionally, the Notice of Award (NoA) will indicate a different due date which will supersede these dates. • MYF: Progress Reports for MYF awards are due annually on or before the anniversary of the budget/project period start date of the award. The reporting period for a MYF progress report is the calendar year preceding the anniversary date of the award. • Final RPPR: Final progress reports are due within 120 days of the end of the period of performance. • Interim RPPR: Interim progress reports are due within 120 days of the end of the period of NIH RPPR Instruction Guide 15 January 2026 IMPORTANT: Do Not Include Personal Identifiable Information (PII) Or Protected Health Information (PHI) In the RPPR Sensitive PII (e.g., Social Security Number, personal financial information, Alien Registration Number) and PHI (e.g., personal medical conditions) require strict handling due to the increased risk to an individual if the data is compromised. Documents containing sensitive PII or PHI must not be included in the RPPR. NIH GRANTS ONLY: Additional information on this topic can be found in this FAQ or by contacting your IC Privacy Coordinator. performance. Interim progress reports are only required when a renewal application (Type 2) has been submitted to the NIH for consideration on or before the due date by which a F-RPPR would be due for a competitive segment. If the Type 2 is not funded, the Interim-RPPR will serve as the Final-RPPR for the project. If the Type 2 is funded, the Interim-RPPR will serve as the annual RPPR for the final year of the previous competitive segment. 3.2 Agency for Healthcare Research and Quality (AHRQ) All AHRQ RPPRs are due 3 months before the anniversary of the award. For example, for an FY2024 award issued with a start date of 2/1/2024, the annual progress report (RPPR) for the award to be issued in FY2025 is due 11/1/2024 (i.e., three months before the FY2025 budget period start date of 2/1/2025). If the due date falls on a weekend or federal holiday, the due date is automatically extended to the next business day. Please note that AHRQ does not participate in the SNAP (Streamlined Noncompeting Award Process) initiative. AHRQ recipients are to submit detailed budgets for the parent organization and for each consortium involved in the project. 4 Data Entry, PDF Attachments, and Style 4.1 Data or Text Box, and PDF Size Limits Most text entry boxes have an 8,000 character limit (~3 pages); this limit is standardized across federal agencies implementing the RPPR and entry of more than 8,000 characters is prevented by the system. In an effort to reduce recipient burden and encourage concise responses, NIH has stated the recommended length of the response for some questions and, for agency-specific questions, has limited text box responses to less than 8,000 characters. AHRQ recipients should follow NIH recommended lengths for text entries. Warning: Text exceeding 8,000 characters is cut to 8,000 when using the cut and paste feature. PDF file uploads (attachments) do not have page limits but may not be more than 6 megabytes (6MB). PDF attachments are utilized when there may be a need for a recipient to provide considerable detail (e.g., change in human subject protocols that requires a new or revised Protection of Human Subjects section as described in the NIH How to Apply - Application Guide ). Even when developing PDF responses, recipients are encouraged to be concise and avoid unnecessary detail. 4.2 PDF Attachments Recipients should generate text attachments using any word processing software and then convert those files to PDF before attaching the files to the appropriate section in the progress report. Unless otherwise stated in the instructions, PDF files uploaded to RPPR are required to be flattened PDFs; see more information on flattened PDFs. Recipients should note that Common Forms (Biosketch and Current & Pending (Other) Support Forms) in most cases should NOT be flattened, to retain signature validations NIH RPPR Instruction Guide 16 January 2026 created in SciENcv. The PDF format is used to preserve document formatting. All PDF attachments must be submitted as individual files. Although some software packages allow bundling of multiple PDFs into a single file, eRA systems cannot support “Bundling” or “Portfolio” features at this time. Use of these features may result in delays in agency acceptance of the progress report. Paginated PDF files are also discouraged since they can interfere with system pagination of the entire RPPR document upon submission to the agency. File names will be used and displayed in the assembled PDF submitted to the agency. Save all files with descriptive file names of 50 characters or less and be sure to only use standard characters in file names: A through Z, a through z, 0 through 9, and underscore (_). Do not use any special characters (example: &, -, *, %, /, and #) or spacing in the file name, and for word separation use an underscore (e.g., My_Attached_File.pdf). Use an Arial, Helvetica, Palatino Linotype, or Georgia typeface, a black font color, and a font size of 11 points or larger. (A Symbol font may be used to insert Greek letters or special characters; the font size requirement still applies.) Type density, including characters and spaces, must be no more than 15 characters per inch. Type may be no more than six lines per inch. Use standard paper size (8 ½" x 11). Use at least one-half inch margins (top, bottom, left, and right) for all pages. No information should appear in the margins, including the PD/PI’s name and page numbers. 4.3 Style Use English and avoid jargon. Abbreviations and language that may not be known to the broader scientific community should be avoided unless clearly defined. Internet Web site addresses (URLs) should not be used unless otherwise specified in the RPPR instructions. 5 Navigation The RPPR is completed using the eRA Commons system. The report in Commons consists of separate screens for each of the sections listed below: • A Cover Page • B Accomplishments • C Products • D Participants • E Impact • F Changes • G Special Reporting Requirements • H Budget • I Outcomes To open an RPPR for editing, users go to the RPPR module, click an Award Number on the Manage RPPR screen, click the three-dot ellipsis icon next to Award Number on the RPPR Menu screen, and select Edit RPPR. Users may work on various sections in any order; however, it is important to click the Save button in the navigation bar before leaving a screen in order to retain data entered on that screen. Upon submission to the awarding agency, the system will generate a PDF of the progress report, which may be viewed from the RPPR Menu screen using the View button. NIH RPPR Instruction Guide 17 January 2026 Once submitted, the final RPPR, in PDF format, is accessible in Commons via the Status Information screen. Refer to the section titled Viewing the Completed RPPR in Commons for detailed steps. Note that a link to a site outside the RPPR (e.g., U.S. Select Agency Registry in F.3.d, or the NIH human embryonic stem cell Registry in G.6) opens a site in a new browser window. You must close that window to return to the RPPR. Do not close the browser or use the browser’s back button. 5.1 Initiate the RPPR Only the PD/PI or the PD/PI delegate may initiate an RPPR. When there are multiple PIs (MPI), only the Contact PI or the PD/PI delegate of the Contact PI may initiate the report. To initiate, the user can choose from one of two ways to access the RPPR functionality: 1. Access RPPR from Status: a. Select Status from the eRA Commons Main menu or click the Status button on the eRA Commons Home screen. b. Click the List of Applications/Awards header on the Status screen. Figure 1 Figure 1 RPPR Navigation Links from Cover Page NIH RPPR Instruction Guide 18 January 2026 Figure 2 Status Screen for PIs, showing List of Applications/Awards c. From the Status Result – List of Applications/Awards screen, locate the award and click the RPPR button in the Available Actions column for the specific award. The RPPR button for the current reporting period is available once the Notice of Award for the prior year has been issued. This link remains available until the RPPR for the current reporting year has been submitted. For multi-year funded awards, the link will display as RPPR Year <X>, the <X> representing the reporting year. The link for a multi-year funded award is available two months prior to the RPPR due date for the current reporting period and remains available until the RPPR is submitted. Note that AHRQ has not yet implemented the RPPR for multi-year funded awards. NOTE: While RPPR Year <X> links for multiple years may appear at the same time in Status, you are prevented from initiating a reporting year’s progress report until the progress report(s) of the previous year(s) has been submitted. NIH RPPR Instruction Guide 19 January 2026 Figure 3 RPPR Button on Status Result – List of Applications/Awards Figure 4 Multi-Year Award RPPR Link NIH RPPR Instruction Guide 20 January 2026 –OR– 1. Access RPPR from the RPPR module: a. Select RPPR from the eRA Commons Main menu. The Manage RPPR screen displays. Manage RPPR is used to view the progress reports to which the user has access and allows the user to select a progress report in order to perform various actions. PD/PIs or users delegated PD/PI progress report authority use the Manage RPPR screen to view their own progress reports. SOs and AOs use the screen to search for grants from their organization and/or for awards routed to them for review. b. Select the specific grant by clicking the linked Award Number on the Manage RPPR screen. If an RPPR exists already, Commons displays the report for editing. The RPPR Menu screen displays. The options for the uninitiated report are Initiate and Cancel. Once an RPPR is in progress, other options are enabled. These options are discussed later, following the steps for initiation. NOTE: For multi-year funded awards, the following message displays when attempting to initiate an RPPR if the previous year’s report has not been submitted: The Multi-Year RPPR for the previous year must be submitted prior to initiating this Multi- Year RPPR. The RPPR Menu screen includes the following fields: Award Number This is the complete number of the grant PD/PI Name The PD/PI of the grant award for which the progress report is being prepared. In the case of MPIs, a list Figure 5 Manage RPPR List of Applications/Awards NIH RPPR Instruction Guide 21 January 2026 of PD/PI names displays with the Contact PD/PI indicated by the word Contact. Project Title The project title of the grant Due Date NIH The due date of the progress report for awards issued under the SNAP (Streamlined Noncompeting Award Process) provisions is the 15 th of the month preceding the month in which the budget period ends (e.g., if the budget period ends 11/30, the due date is 10/15). If the award is not issued under SNAP provisions, the progress report is due the first of the month preceding the month in which the budget period ends (e.g., if the budget period ends 11/30, the due date is 10/1). If the due date falls on a weekend or federal holiday, the due date is automatically extended to the next business day. Progress reports for Fellowships are due two months before the beginning date of the next budget period. Occasionally the Notice of Award (NoA) will indicate a different due date which will supersede these dates. Recipients should consult the NoA to determine when SNAP procedures apply. AHRQ All AHRQ RPPRs are due 3 months before the anniversary of the award. For example, for an FY2024 award issued with a start date of 2/1/2024, the annual progress report (RPPR) for the award to be issued in FY2025 is due 11/1/2024 (i.e., three months before the FY2025 budget period start date of 2/1/2025). If the due date falls on a weekend or federal holiday, the due date is automatically extended to the next business day. Current Reviewer The name of the current reviewer or organization (e.g., PD/PI name, NIH). This value is blank before the RPPR is initiated. Status The current state of the progress report. Possible values are as follows: Not Started, PD/PI Work in Progress, Reviewer Work in Progress, and Submitted to Agency. Initiate button: Begins the RPPR process. Available for grants with a status of Not Started. Access is granted to PD/PIs and PD/PI delegates. An RPPR can be initiated even if required information in the Personal Profile and Institution Profile sections is missing. If any of this information is incorrect or missing, a prompt will appear to correct/complete the information after initiating the report. Processing may continue on the RPPR without making the corrections; however, the RPPR will not pass validations for submission to the agency until the errors are corrected. NOTE: A PD/PI with Progress Report authority cannot submit a non-SNAP or F RPPR. Cancel button: Closes the RPPR Menu screen and returns the user to the previous screen. 2. Click the Initiate button to begin the RPPR. NIH RPPR Instruction Guide 22 January 2026 Figure 6 RPPR Menu for Initiating the Report Once initiated, Commons creates the report in a PD/PI Work in Progress status and sets the current reviewer. A message displays as follows: The RPPR has been successfully initiated. NOTE: If initiation fails due to business rules validations, error or warning messages display on the screen. Once initiated, begin editing by clicking the three-dot ellipsis icon next to Award Number and selecting Edit RPPR. The RPPR is accessed for editing via the RPPR Menu screen. The editing feature for single- project RPPRs is different from those of multiproject RPPRs. The steps for accessing each type of RPPR are outlined in the sections that follow. Refer to Accessing the RPPR From Closeout, Accessing a Single-Project RPPR for Editing or Accessing a Multi-Project and Single-Project with Complicated Structure RPPR for Editing as appropriate. After a RPPR is initiated, several actions appear under the three-dot ellipses icon next to Award Number on the Manage RPPR screen. Available actions vary depending on the status of the RPPR and/or the limitations of the current user’s role. The possible available actions include the following: • Edit RPPR: Click the three-dot ellipsis icon next to Award Number and select Edit RPPR to open the RPPR for edits. Available for progress reports with a status of Work in Progress (WIP). Access is granted to PD/PIs or PD/PI delegates when the PD/PI is the current reviewer, AOs when the AO is the current reviewer, and SOs when the SO is the current reviewer. The Edit RPPR option allows the user to view and edit RPPR information. • View RPPR as PDF: Click the three-dot ellipsis icon next to Award Number and select View RPPR as PDF to open the RPPR report in PDF format, as it will be seen by the agency. Available for progress reports with a status of Work in Progress (WIP) or Submitted to Agency. Access is granted to PD/PIs, PD/PI delegates, and reviewers. Until the RPPR is submitted to agency, the PDF report shows a status of Draft and a blank submission date. • Check for Errors: Click the three-dot ellipsis icon next to Award Number and select Check for Errors to check the RPPR for any errors or warnings. Available for progress reports with a status of Work in Progress (WIP). Access is granted to any user with access to the grant. The RPPR can be validated at any time while in the status of WIP and can be validated multiple times. NIH RPPR Instruction Guide 23 January 2026 • View Routing History: Click the three-dot ellipsis icon next to Award Number and select View Routing History to open a page that displays a routing history table. Available for progress reports with a status of Work in Progress (WIP) or Submitted to Agency. Access is granted to PD/PIs, PD/PI delegates, and reviewers. • Route to Next Reviewer: Click the three-dot ellipsis icon next to Award Number and select Route to Next Reviewer to route the RPPR to the next reviewer for further review or corrections. Available for progress reports with a status of Work in Progress (WIP). Access is granted to the current reviewer. A PD/PI delegate cannot route an RPPR to the next reviewer. • Recall: Click the three-dot ellipsis icon next to Award Number and select Recall to recall RPPRs that have been forwarded to another reviewer and resets the user as the current reviewer. Available for reports with a status of Work in Progress (WIP). Access is granted to the last reviewer (who recalls the report from the current reviewer). Signing Officials and PD/PIs can recall an RPPR even if they are not the last reviewer whenever it has a status of Reviewer Work in Progress. This is useful in situations when a RPPR has been routed to the wrong person or to someone who is unavailable. • Submit: Click the three-dot ellipsis icon next to Award Number and select Submit to submit the RPPR to the Agency. Available for reports with a status of Work in Progress (WIP). Access is granted to the SO when the SO is the current reviewer and to the PD/PI when the PD/PI has been delegated Progress Report authority. 5.2 Accessing the RPPR From Closeout You can access the RPPR from Closeout. The following procedure is from the point of view of a Principal Investigator (PD/PI). To access the RPPR from Closeout: 1. Go to the Status module and click the Requires Closeout button in the Available Actions column for an award. NIH RPPR Instruction Guide 24 January 2026 Figure 7 Requires Closeout Button 2. On the Closeout Status screen that appears, click the Process Final RPPR link. Figure 8 Closeout Status Screen NIH RPPR Instruction Guide 25 January 2026 3. On the Final RPPR Menu screen that appears, click the Initiate button to start the RPPR. Figure 9 Final RPPR Menu Once initiated, Commons creates the report in a PD/PI Work in Progress status and sets you as the current reviewer. A message displays as follows: The RPPR has been successfully initiated. 5.2.1 Starting Your Final Research Performance Progress Report As of January 1, 2017, a Final Research Performance Progress Report (Final RPPR) is required for any grant that has ended and any grant that is not to be extended through award of a new competitive segment. The report is due within 120 days of the end of the project period. This report should be prepared in accordance with instructions provided by the awarding component. See NIH Implementation of Final Research Performance Progress Reports (Final RPPR) — Guide Notice NOT-OD-17-022 Effective February 9, 2017, if the recipient organization has submitted a renewal application on or before the date by which a Final Research Performance Progress Report (Final RPPR) would be required for the current competitive segment, then submission of an "Interim RPPR" via eRA Commons is required. The Interim RPPR will be used for the submission of a Competing Renewal application (Type 2). See NIH Implementation of the Interim RPPR while a Renewal Application is Under Consideration — Guide Notice NOT-OD-17-037. Both the Interim RPPR and the Final RPPR are currently identical in process and information required. The difference between the two is when and where they are made available to initiate and submit. The Interim RPPR link will be made available to the Signing Official (SO) in the Status screen when a grant is eligible for submission of a Competing Renewal application. The Final RPPR is only available as part of the Closeout process and the Process Final RPPR link only appears on the Closeout Status screen. The format of the Interim RPPR and the Final RPPR are the same as the annual RPPR, making it easier for recipients to navigate through both the Interim and the Final RPPR, based on familiarity with the format of the annual RPPR. Differences between Interim/Final RPPR and the annual RPPR are few: • In the Interim/Final RPPR, only Section D.1 is required in the Participants section • Sections F: Changes and Section H: Budget are not part of the Interim/Final RPPR • Section I: Outcomes. Section I is required for both the Interim/Final RPPR. Outcomes does not appear in the system for the annual RPPR NIH RPPR Instruction Guide 26 January 2026 Note about Interim RPPR and Final RPPR The Interim RPPR is used when you are submitting a Competing Renewal application (Type 2). If you opt NOT to apply for a Competing Renewal, complete the Final RPPR as you normally would within 120 days of the project end date. If you are going to complete a Competing Renewal application (or have already submitted such an application), you will submit an Interim RPPR. This must be submitted within 120 days of the project end date. If you are awarded the renewal, the Interim RPPR will be treated as your annual RPPR and no other progress reporting will be needed for that segment of the study. If the application is NOT awarded, then the Interim RPPR will be accepted as the Final RPPR. To start your Final RPPR: 1. Select the Requires Closeout link for the grant from Status search results. The Closeout Status screen displays. Final RPPR is listed in the Closeout Submission Requirement column. The Action column should include a button for Process Final RPPR. 2. From Closeout Status, click the Process Final RPPR button. 3. Clicking the Process Final RPPR link opens the Final RPPR Menu screen: 4. Click the Initiate button to create the Final RPPR. The Final RPPR Menu will then change, providing the user with the option to Edit the Final RPPR: 5. Selecting Edit RPPR from the three-dot ellipsis menu opens the navigation to the various sections of the Final RPPR: 6. Complete each section as required. 7. Be sure to click SAVE when moving between sections or unsaved data may be lost. 8. When done, click Cancel to return Final RPPR Menu screen. 9. In the Final RPPR Menu screen, there are several actions in the three-dot ellipsis menu next to the Award Number that you can use to complete the Final RPPR: For more information on these options, see RPPR online help. 5.3 Edit the RPPR Once an RPPR is initiated, its status becomes PD/PI Work in Progress, and it becomes available for editing. The PD/PI or delegate uses the Edit RPPR option in the three-dot ellipsis menu for viewing and completing the report. Additionally, this option is available to the SO or AO when that user is the current reviewer of the report. NOTE: For RPPRs with multiple PD/PIs (MPI awards), only the Contact PD/PI has access to the Edit RPPR option unless the Contact PD/PI has granted progress report authority to other PD/PIs. Without this authority, MPIs can only view the RPPR PDF and its routing history. There are two means of accessing the progress report for editing. These are similar methods used for initiating the report and are as follows: 5.3.1 Access RPPR From Status 1. Select Status from the eRA Commons Main menu. NIH RPPR Instruction Guide 27 January 2026 2. Click the List of Applications/Awards heading on the Status screen. Figure 10 PI view of Status Screen, showing List of Applications/Awards heading NIH RPPR Instruction Guide 28 January 2026 3. From the Status Result – List of Applications/Awards screen, locate the grant and click the RPPR, Interim RPPR, or Final RPPR button in the Available Actions column for the specific award. For multi-year funded awards, the button will display as RPPR Year <X>, the <X> representing the reporting year. Figure 11 RPPR Button on PI’s Status Result – List of Applications/Awards screen Figure 12 Multi-Year Funded Award RPPR Button NIH RPPR Instruction Guide 29 January 2026 5.3.2 Access RPPR From the RPPR Module in eRA Commons 1. Select RPPR from the Commons Main menu. 2. Select the specific grant by clicking the link in the Award Number column on the Manage RPPR screen. SOs/AOs must perform a query first. The appropriate RPPR Menu screen – either for single-project or multi-project RPPRs – displays with editing options. To see the actions available on the RPPR, including the Edit RPPR option, click the three-dot ellipsis icon next to Award Number and a menu appears. 5.3.3 Accessing a Single-Project RPPR for Editing For single-project awards, the RPPR Menu screen displays with a three-dot ellipsis menu next to Award Number. Only those options which are currently possible appear; for instance, if you are editing the RPPR, the Route.. action appears, but not the Recall, whereas if you just routed the RPPR, the Recall action appears, but not the Route.. action. The following options are available either under the three-dot ellipsis menu or as a button: Edit RPPR Check for Errors View RPPR as PDF View Routing History Route to Next Reviewer Cancel button NOTE: Once an RPPR has been routed for review, the Recall action appears in the three-dot ellipsis menu, while the Submit option disappears. These functions are covered in subsequent chapters. Figure 13 Manage RPPR List of Applications/Awards NIH RPPR Instruction Guide 30 January 2026 Figure 14 SO view of RPPR actions under the three-dot ellipsis menu (including Submit action, available to SOs only) Select Edit RPPR from the three-dot ellipsis menu to open the RPPR for editing. Refer to the section of this document titled Editing the RPPR Forms for more information on editing the forms. 5.3.4 Accessing a Multi-Project and Single-Project with Complicated Structure RPPR for Editing A multi-project RPPR is a progress report submitted for a funded program (activity code) which has multiple, interrelated components sharing a common focus or objective. A component (for the purposes of applications and progress reports) is a distinct, reviewable part of the multi-project application or progress report for which there is a business need to gather detailed information identified in the notice of funding opportunity (NOFO). Components typically include general information (component organization, project periods, project title, etc.), performance sites, personnel, and budget. The NOFO defines the construction and naming convention for the application; the funded application defines the construction and naming convention for the progress report. For multi-project awards, the RPPR Menu screen displays the following available options under the three-dot ellipsis icon on the top section of the screen: View RPPR as PDF View Routing History Route to Next Reviewer Cancel button NOTE: Once an RPPR has been routed for review, the Recall and Submit buttons are enabled. These functions are covered in subsequent chapters. NIH RPPR Instruction Guide 31 January 2026 Figure 15 RPPR Menu Options for Multi-Project RPPRs Overall Below the Overall RPPR is a table showing components. For multi-component awards, the Yes radio button on the Has Components? field is selected. The RPPR Menu for a multi-project RPPR without components does not include the component table and the No radio button is selected for Has Components? To edit the RPPR for the Overall, click the three-dot ellipsis menu for the overall award in the top section of the screen below) and select Edit RPPR. NIH RPPR Instruction Guide 32 January 2026 Figure 16 Edit Option for Overall Individual Components If the award has individual components (e.g., a multi-project award), each component must be reported in the RPPR. To add components, select the Yes radio button next to the question Has components? Selecting Yes displays the Add Component button for the individual components. NOTE: Any individual components previously added will already be displayed in a table beneath this feature. In this scenario, the “Has Components?” option is set to Yes and disabled. This includes components which were part of a previously submitted progress report for the grant. To add an individual component: 1. Click the Add Component button and select New Component from the button dropdown. The Add New Component popup appears. NIH RPPR Instruction Guide 33 January 2026 Figure 17 Add New Component Popup 2. Enter the Component Project Title and select a Component Project Type from the dropdown. 3. Click the Add Component button in the popup. Added individual components display in a table beneath the Overall, showing the ID, Date, Type, Title, and available actions under the three-dot ellipsis icon. 4. To edit a component’s RPPR, click its three-dot ellipsis menu, and select Edit RPPR. Refer to the section of this document titled Editing the RPPR Forms for more information on editing the RPPR forms. Individual components can be removed from the RPPR by clicking that component’s three-dot ellipsis menu and selecting Delete; the component is deleted immediately. The delete option is not available for Overall. IMPORTANT: If you choose to delete a component, all data related to this component – including all budget data – will be lost. This data cannot be recovered once it has been deleted. 5.3.5 Editing the RPPR Forms After selecting the appropriate editing option, the RPPR section A. Cover Page displays. The Cover Page includes information about the award, PD/PI, signing and administrative officials, organization, and project/reporting/budget periods. Some of this information is auto- populated. For more information on the Cover Page, refer to the section of this document titled Section A – Cover Page located in the Instructions for RPPR Sections A–I. 1. Update the information as necessary and select the Save button. The Cover Page includes tabs at the top and links at the bottom of the page for navigating to the other sections (e.g., Accomplishments, Participants), which may be completed in any order. Before navigating to and from any of these sections, it is always necessary to select the Save NIH RPPR Instruction Guide 34 January 2026 button to save all changes on the current page. Navigating away from any page on the RPPR without selecting Save results in the loss of any information entered prior to the last save. 2. Sections can be completed in any order. To navigate and populate the other sections of the RPPR, select the appropriate link from the top or bottom of the page. The same navigational links appear on each section of the RPPR. For information on the specific fields in each section refer to Chapter 6 Instructions for RPPR Sections A–I. 3. Complete the appropriate fields of the report. Details for completing each section are discussed later in this document. Many of the fields on these pages, however, behave in a similar manner and are discussed below. + Add Button To use an Add button, click it to see a popup, then enter or select data into the appropriate fields. Figure 18 RPPR Cover Page and Section Navigation Links NIH RPPR Instruction Guide 35 January 2026 Figure 19Add Button and Edit and Delete actions available from the three-dot ellipsis menu in a table Items can be edited or deleted from the table using the Edit and Delete actions under the three-dot ellipsis menu. Text Box All text boxes on the RPPR have character limits. The number of characters available is reflected beneath each text box as characters are entered. Changing Saved Responses While an RPPR is in Work In Progress status, answers may be changed. A warning message displays as follows: The entered/uploaded response will be deleted. Do you wish to continue? The user editing the information can choose to Continue or Cancel the action. Choosing Continue deletes the previous response, removes any attachments, and disables the relevant fields associated with the question. Choosing Cancel cancels the change. 1. Select the Save button before navigating to the next page. 2. To return to the RPPR Menu, select the Cancel button. When an RPPR is ready for review and submission, it is routed to the next reviewer. Only a signing official (SO) can submit. Refer to the section of this document titled Route the RPPR for steps on routing to the next reviewer. Figure 20Total Remaining Characters NIH RPPR Instruction Guide 36 January 2026 Table Tools You might notice various icons above tables in RPPR. Several built-in table tools let you work with data in tables. For an explanation of all table tools, see Standard Tools for Tables in the online help topic, Basics and Navigation for eRA Modules. Filter Entering filter text to see instant filtering of the list as you type, with the number of found results updated as you type. The text you type in filter is highlighted in the table. Sorting Columns Click column headers to sort by that column. Gray up and down triangles indicate a non-sorted column. A solid black up arrow indicates the table is sorted by that column-descending and solid black down arrow indicates the table is sorted by that column-ascending. Download/Print Tool Use the download tool to export table data to Excel or PDF, or to print. Data from all columns is exported/printed even if only a subset of columns are visible. Rows-Per-Page Tool Figure 21Standard Table Tools Figure 22Filter Table Field Figure 23Column Sort Options Figure 24 Download Tool Figure 25 Rows-per-Page Tool NIH RPPR Instruction Guide 37 January 2026 IMPORTANT: Before selecting the Human Subjects link, click the Save button on the RPPR to save all of your work in Section G. Failure to do so will result in a loss of data on your report. To help avoid scrolling, use the Rows-per-Page tool to specify how many table rows appear per page. Search Results Navigation Navigate to each page of search results using the above tool. 5.3.6 Editing Inclusion Enrollment Data The following section is intended for NIH award recipients only and discusses inclusion data in the Human Subjects System (HSS) as accessed and processed via your RPPR. For more information on HSS, please refer to the HSS Online Help or the HSS Training website. To update inclusion enrollment data, select the Human Subjects link from question G.4 of section G. Special Reporting Requirements. For additional information on inclusion procedures in the RPPR, please review Section G – Special Reporting Requirements. The Human Subjects link will take you to the Application Information screen. Click on the HSCT Post Submission tab. This will take you to the Study Record(s) screen that displays all the study records and delayed onset records for the grant. You may view the information within a study record, including the last inclusion enrollment report (IER) by clicking on the View button under the Action column within the list of study records. To edit the inclusion information, click the Edit button at the top of the screen. You will now see an Edit button under the Action column within the list of study records. Click on this Edit button to make changes to the study record information, including the inclusion enrollment data. Figure 26 Navigation Tools Figure 27 Human Subjects Link in Question G.4 NIH RPPR Instruction Guide 38 January 2026 Figure 28 Manage IERs for Single Project The Inclusion Enrollment Report (IER) is within the Study Record and can be found in Section 2- Study Population Characteristics. Here, you can add a new inclusion enrollment report or edit a report that was previously created. NIH RPPR Instruction Guide 39 January 2026 Figure 29 Adding/Editing an Inclusion Enrollment Report Select the Edit button in the Action column to edit the Inclusion Enrollment Report. The Inclusion Enrollment Report screen contains the following information: Inclusion Enrollment Report Fields • Using an Existing Dataset or Resource Displays Yes/No as indicated by radio buttons • Enrollment Location Type Displays Domestic/Foreign as indicated by radio buttons • Enrollment Country(ies) Displays the country of enrollment as identified from a dropdown list • Enrollment Location(s) Displays a location entered by the user. • Comments An optional text field for entering cumulative enrollment comments. If any comments for cumulative form were entered before, this field is pre-populated when editing an existing IER. See the application guide instructions for more information about Inclusion Enrollment report fields. NIH RPPR Instruction Guide 40 January 2026 Figure 30 Inclusion Enrollment Report Fields The cumulative enrollment table includes racial categories along the left side the of the table and ethnic categories, divided by sex, along the top of the table. The individual enrollment count cells are editable and set to zero by default, when populating a new IER. When editing an existing form, these values are pre-populated with any other value previously entered. The total fields are calculated by HSS and sum up as rows and columns accordingly. The total values are not editable fields. NOTE: The cumulative inclusion table includes fields for entering Unknown/Not Reported race, ethnicity, and sex data. There are two ways to edit the existing Inclusion Enrollment Report (IER) data for Cumulative (Actual) counts: 1. You can update the cells online in the existing report itself. 2. You can download a template for entering participant-level data by clicking on the Download Participant Level Data Template button. This will download a spreadsheet file in the proper CSV format to be used by the system. • Fill the template out with data, save the changes, and then upload the spreadsheet by clicking on the Upload Participant Level Data Attachment button. This uploaded data will populate the cells in the report. • You can click on the Download Current Participant Level Data button to download the file containing the data for your own records. • If you need to clear the current records, use the Remove Current Participant Level Data button. Update the values in the individual enrollment count cells as necessary, and select the Save and Release NIH RPPR Instruction Guide 41 January 2026 Lock button. To leave the form without saving any changes, select the Cancel and Release Lock button instead. Saving and canceling both return you to the Study Record(s) screen. POLICY: Individual-level participant data on sex, race, ethnicity and age at enrollment is required in progress reports for competitive applications submitted for due dates on or after January 25, 2019 (See NIH Guide Notice NOT-OD-18-116). Inclusion data for subsequent RPPRs must be provided using the file upload option. Figure 31 Cumulative (Actual) Enrollment Table NIH RPPR Instruction Guide 42 January 2026 5.2.4.1 Changes to Planned Enrollment If there are changes from the planned enrollment originally approved for funding, contact the program officer to discuss updating/revising the planned enrollment. See Section G – Special Reporting Requirements of this guide for more information. From the Study Record(s) screen, select the Edit link in the Action column of the Inclusion Enrollment Report section to edit the Inclusion Enrollment Report. The planned enrollment table includes racial categories along the left side of the table and ethnic categories, divided by sex, along the top of the table. The individual enrollment count cells are editable and set to zero by default, when populating a new IER. When editing an existing form, these values are pre-populated with any other value previously entered. The total fields are calculated by HSS and sum up as rows and columns accordingly. The total values are not editable fields. POLICY: For additional information on racial and ethnic categories or inclusion policy, refer to Inclusion of Women and Members of Racial and/or Ethnic Minority Groups in Clinical Research and FAQs on Inclusion – Basis of Sex and Race and/or Ethnicity. Update the values in the individual enrollment count cells as necessary and select the Save and Release Lock button. To leave the form without saving any changes, select the Cancel and Release Lock button instead. Saving and cancelling both return you to the Study Record(s) screen. 5.2.4.2 No Inclusion Data Records Provided When inclusion monitoring is required and no IERs exist, RPPR system will NOT allow the submission of the progress report without IER(s). For the current FY it will display an error message and require that you submit a new enrollment record. This is true for the current FY of a multi-year award as well. For the past FYs (when the progress report is late), a standard message is displayed in lieu of the error message as follows: NIH policy requires inclusion to be monitored, but no inclusion data record(s) (IERs) have been provided. This standard message will appear on both the screen and the PDF version of the progress report. Submit New Planned Inclusion Record From the Study Records(s) screen, select the Add New Inclusion Enrollment Report to create a new IER. If no study records exist, first add a study record using instructions in the online help. Upon a successful save of a new IER, attributes (Foreign/domestic indicator/planned comments), Planned Inclusion Data (as entered), and Cumulative Inclusion Data (as zeros) are also created; the new IER is assigned a unique IER #. 5.3.7 Editing the RPPR Budget Forms Budget Form (H.1) To add a budget, choose an option from the drop-down list and click the Add Budget button. The added budget type appears in the first table. Click the budget’s three-dot ellipsis menu and select Edit to open the form for editing. Most awards now use the SF424 R&R budget form. However, training awards may use the SF424 and/or the PHS 398 training budget. The PHS Additional Indirect Costs budget form is available as an optional form for the Overall component of a multi-project award with multiple organizations. Please contact the Grants Management Specialist assigned to your grant if you have questions on the appropriate form to use. NIH RPPR Instruction Guide 43 January 2026 Budget types include: • SF 424 Research & Related Budget form • PHS 398 Training Budget • PHS Additional Indirect Costs form NOTE: Budget types can be deleted by clicking the budget’s three-dot ellipsis icon and selecting Delete. After deleting a form, be sure to save the RPPR before navigating away from the H.Budget tab. The Save button is at bottom of the screen. Subaward Budget Form (H.2) To add a subaward budget, choose an option from the drop-down list and select the Add Subaward Budget button. A table appears listing the subaward budget you added. To edit the subaward budget, click its three-dot ellipsis icon and select Edit, which opens the form for editing. Click the Save button before exiting the form. Subaward budget types include: • SF 424 Research & Related Subaward Budget form • PHS 398 Subaward Training Budget The recipient may select up to 30 subaward budgets. NOTE: Subaward budget types can be deleted by clicking the subaward’s three-dot ellipsis icon and selecting Delete. NIH RPPR Instruction Guide 44 January 2026 Figure 32 RPPR H. Budget - Questions H.1 Budget Form & H.2 Subaward Budget Form NOTE: Remember to save the information before exiting the form by clicking the Save button at bottom of the form. For single-component awards, and for the OVERALL component of a multi-component award, the UEI automatically populates the Unique Entity Identifier and Organization Name fields of the recipient organization on the budget form, but these fields are NON-editable. For a multi-component award, the component’s UEI and organization name are prepopulated with the recipient organization’s data, but both the Unique Entity Identifier and Organization Name fields are editable, so you can choose to change them. NIH RPPR Instruction Guide 45 January 2026 Figure 33 Organizational UEI on SF 424 Research & Related Budget To change either the UEI or the organization name associated with this budget: 1. Click one of the magnifying glass icons next to the Unique Entity Identifier (UEI) or Organization Name fields. The Search Organization popup appears. Figure 34 Search Organization popup window NIH RPPR Instruction Guide 46 January 2026 2. Enter information in either field (Unique Entity Identifier or Organization Name) and click Search. A list of matches appears. NOTE: If no matches appear, you can click the Add New Organization button to type the UEI and organization name manually and click Save. Whatever you entered will then populate the Unique Entity Identifier or Organization Name fields. 3. Select the organization you are searching for and click Save. Both the Unique Entity Identifier and Organization Name field are updated with the information of the organization you selected. NOTE: If subaward budgets are completed, the system will not calculate the budget line item F.5 for the main budget (see figure below). Total consortium costs for the main budget MUST be computed and entered manually into budget line item F.5. Figure 35 SF 424 R&R Budget Form - Question F.5 NIH RPPR Instruction Guide 47 January 2026 5.4 Check RPPR for Errors and Warnings At any time before an RPPR is submitted to agency, an error check can be performed to verify that the report passes the business rules and system validations in place. Any user who has access to the RPPR may perform the error check. 5.4.1 Checking for Errors on Single-Project RPPRs To perform an error check on the RPPR for single-project RPPRs, click the three-dot ellipsis menu next to the Award Number and select Check for Errors. Figure 36 Check for Errors option on RPPR Menu for a Single-Project RPPR If errors or a warning exist, the appropriate error or warning message displays for each failed occurrence. All errors must be corrected prior to submission; the system will prevent submission of an RPPR containing errors. However, the system will not prevent submission of an RPPR when a warning message is displayed. If all validations pass, a message displays indicating: No errors found on validation. 5.4.2 Checking for Errors on a Multi-Project RPPR To perform an error check on the Overall or individual component of a multi-project RPPR, select the Check for Errors option from the three-dot ellipsis menu on the RPPR Menu screen for the Overall or individual component being validated. NOTE: Refer to section Accessing a Multi-Project and Single-Project with Complicated Structure RPPR for Editing for information on adding individual components to the RPPR. Figure 37 RPPR Error Messages (Examples) NIH RPPR Instruction Guide 48 January 2026 Figure 38 Check for Errors Link for Multi-Project RPPRs If errors or a warning exist for the chosen component, the appropriate error or warning message displays for each failed occurrence. Select the Check for Errors option for the other components to perform a check against them. All errors must be corrected prior to submission; the system will prevent submission of an RPPR containing errors. However, the system will not prevent submission of an RPPR when a warning message is displayed. If all validations pass, a message displays indicating: No errors found on validation. 5.5 Route the RPPR Progress reports in Work in Progress (WIP) status can be routed to others for review or corrections by the current reviewer of the report. The routing feature is found on the RPPR Menu screen. Figure 39 Errors and Warnings for One Component of a Multi-Project RPPR NIH RPPR Instruction Guide 49 January 2026 NOTE: A person who is delegated a role of PD/PI cannot route an RPPR to the next reviewer. To route an RPPR to the next reviewer: 1. On the RPPR Menu screen, click the three-dot ellipsis icon and select Route to Next Reviewer. NOTE: The figure above shows the RPPR Menu for a single-project RPPR, however, multiproject RPPRs have a similar Route option on their own RPPR Menu screen. The Route RPPR to Next Reviewer screen displays. From this screen, the next reviewer can be chosen from a list of reviewers, and comments can be added. 2. Select a reviewer from the Next Reviewer dropdown. 3. Optional: Enter comments in the Comments field to provide information to the next reviewer. 4. Required for PD/PI ONLY: Click the checkbox that certifies statements are true. Signing officials do not see the “I certify that the statements herein are true…” checkbox. Figure 40 RPPR Menu – Route Option Figure 41 Route RPPR to Next Reviewer NIH RPPR Instruction Guide 50 January 2026 5. Click the Route to Next Reviewer button. Figure 42 Route RPPR to Next Reviewer Success Message A success message appears. Click the Close link in the success message and the RPPR Menu displays once again. The person who routed the RPPR can no longer edit the report (the Edit RPPR option disappears from the three-dot ellipsis menu). The editing feature is now available only to the new reviewer. The RPPR status is updated to Reviewer Work in Progress. 5.6 Recall the RPPR RPPRs that have been routed to a reviewer can be recalled by the person who performed the routing action. This is useful in situations when the report was routed to the wrong person or the reviewer is unavailable. The last reviewer of the report is able to recall it; however, Signing Officials at the Organization and the Contact PD/PI who are not the last reviewer can also recall the report when it is in a status of Reviewer Work in Progress. NOTE: A person who has been delegated the PD/PI role does not have the ability to recall the RPPR. To recall an RPPR, on the RPPR Menu screen, click the three-dot ellipsis icon and select Recall. The Recall option is only present if you routed the RPPR or if you are an SO and the RPPR is currently in status of Reviewer Work in Progress. Figure 43 RPPR Menu – Recall Option NIH RPPR Instruction Guide 51 January 2026 A message displays indicating: The RPPR has been successfully recalled. You have been set as the Current RPPR Reviewer. The status of the RPPR is updated to PD/PI Work in Progress or Reviewer Work in Progress, the reviewer from whom the RPPR is recalled receives an email about this action, and the RPPR routing audit history is updated to reflect the action. Additionally, the Edit RPPR and Route to Next Reviewer options appear under the three-dot ellipsis menu, providing the new reviewer with the ability to continue editing the RPPR or to route it to another reviewer. 5.7 Submit the RPPR to Agency Recipients are strongly encouraged to view the RPPR prior to submission to ensure that the correct information and attachments are provided (see View the RPPR). Completed and validated RPPRs in a status of Work in Progress can be submitted to the Agency for acceptance. This act is performed by the Signing Official (SO) when the SO is the current reviewer of the report. For SNAP awards only, PD/PIs may also submit the report if they have been delegated submit authority by the SO. NOTE: A PD/PI with Progress Report authority cannot submit a non-SNAP or F RPPR. To submit the RPPR to agency: 1. Click the three-dot ellipsis menu for an RPPR and select Submit. You can do this from the RPPR Menu, Interim RPPR Menu, or Final RPPR Menu screens. Figure 44 RPPR Successfully Recalled Figure 45 Submit Option on RPPR Menu NIH RPPR Instruction Guide 52 January 2026 The Submit RPPR to Agency screen displays a certification statement as follows: In submitting this RPPR, the SO (or PD/PI with delegated authority), certifies that, for all clinical trials funded under this NIH award, the recipient and all investigators conducting NIH- funded clinical trials are in compliance with the recipient's plan addressing compliance with the NIH Policy on Dissemination of NIH-Funded Clinical Trial Information. Any clinical trial funded in whole or in part under this award has been registered in ClinicalTrials.gov or will be registered not later than 21 calendar days after enrollment of the first participant. Summary results have been submitted to ClinicalTrials.gov or will be submitted not later than one year after the completion date, even if the completion date occurs after the period of performance. - OR – In submitting this Progress Report, the SO (or PD/PI with delegated authority), certifies that the awardee organization is in compliance with the terms and conditions specified in the Notice of Award and Awards Policy Statement, and verifies the accuracy and validity of all administrative, fiscal, and scientific information in the progress report. The SO (or PD/PI with delegated authority) further certifies that the awardee organization will be accountable for the appropriate use of any funds awarded and for the performance of the award-supported project or activities resulting from the progress report. Deliberate withholding, falsification, or misrepresentation of information could result in administrative actions such as withdrawal of a progress report, suspension and/or termination of an award, debarment of individuals, as well as possible criminal penalties. The awardee institution may be liable for the reimbursement of funds associated with any inappropriate or fraudulent conduct of the project activity. 2. Click the I Agree button to sign off on the certification. The RPPR [Interim-RPPR or Final RPPR] is validated for systemic and business rules. If there are any validation failures, they are indicated by error messages on the RPPR Menu screen. Errors must be corrected in order to submit the RPPR [Interim-RPPR or Final RPPR]. If warnings exist, they are displayed on the RPPR Menu screen. Although the RPPR can be submitted with warnings present, the warning messages should be reviewed to determine if an issue should be addressed. 3. If Warnings Exist: To address issues associated with warnings, click the Cancel button, correct the issue, and resubmit the RPPR again. To continue with submission despite the warnings, click the OK button. If all validations pass, the RPPR Menu screen displays the following message: The RPPR [Interim-RPPR or Final RPPR] has been successfully submitted. NIH RPPR Instruction Guide 53 January 2026 Figure 46 Successful Submission Message The current reviewer is updated to Agency, the RPPR status is updated to Submitted to Agency, and the RPPR Submission date is recorded. The routing history is updated to reflect the submission to Agency. Any citations associated with the RPPR in “C.1. Publications” are officially associated with the award in MyNCBI. When an RPPR is submitted to the Agency, an email notification is sent to the PD/PI (Contact PI) on the award and the SO and AO assigned to the RPPR. 5.7.1 Submission Errors and Warnings for Multi-Project RPPRs Upon submission, multi-project RPPRs are validated for systemic and business rules just as are single- project RPPRs. However, for multi-projects, the errors and warnings are displayed differently. When errors and/or warnings are found on multi-project RPPRs, the RPPR Menu screen displays the Overall messages followed by the messages of the other components. All errors must be corrected to submit the RPPR. If warnings exist, they are displayed on the RPPR Menu screen under the errors. Although the RPPR can be submitted with warnings present, the warning messages should be reviewed to determine if an issue should be addressed. Figure 47 Sample of Multi-Project RPPR Error Messages NIH RPPR Instruction Guide 54 January 2026 5.8 View the RPPR As indicated in Submit the RPPR to Agency, recipients are strongly encouraged to view the RPPR prior to submission to ensure that the correct information and attachments are provided (see Submit the RPPR to Agency). PD/PIs, PD/PI delegates, and reviewers can view a PDF version of an RPPR in Work in Progress (WIP) or Submitted to Agency status to see how it will be seen by the Agency. Until the RPPR is submitted to agency, the PDF report shows a status of Draft and a blank submission date. To view the RPPR form: 1 On the RPPR Menu screen, click the three-dot ellipsis icon and select View RPPR as PDF. 5.9 View Routing History From initiation to submission to Agency, the routing of an RPPR is captured for auditing purposes. PD/PIs, PD/PI delegates, and reviewers can view the routing history for Work in Progress or Submitted to Agency RPPRs at any time, even when they are not the current reviewer. To view the routing history: 1. On the RPPR Menu screen, click the three-dot ellipsis icon and select View Routing History. Figure 48 RPPR Menu – View the RPPR Option Figure 49 RPPR Menu – View Routing History Option NIH RPPR Instruction Guide 55 January 2026 The RPPR Routing History screen displays showing the Reviewer Name, Action Taken, Notification Sent (date and time), Date of Action, Next Reviewer Name, and Comments (when available). Figure 50 RPPR Routing History 2. To close the screen, click the Close link. 5.10 Viewing the Completed RPPR in Commons The completed RPPR, in PDF format, is accessible in Commons from the Status Information screen. To view the completed RPPR, perform the following steps: 1. From Commons, select Status from the Main menu. 2. Select the heading for List of Applications/Awards. Figure 51 PI view of Status, showing the List of Applications/Awards NIH RPPR Instruction Guide 56 January 2026 3. From the Status Result – List of Applications/Awards screen, select the hyperlink for the specific Application ID. The Status Information screen displays with the Other Relevant Documents section. 4. The progress reports for incrementally-funded and multi-year funded awards are displayed differently in Other Relevant Documents. a. For an incrementally-funded RPPR: Select the e-Application link from the Other Relevant Documents section of the Status Information screen. Figure 52 Application/Award ID link NIH RPPR Instruction Guide 57 January 2026 Figure 53 Status Information Screen – e-Application Link b. For multi-year funded awards: Select the appropriate year’s link in the Research Performance Progress Report section. Links will appear as follows: RPPR Year <X> <MM/DD/YYYY> NIH RPPR Instruction Guide 58 January 2026 Figure 54 Status Information Screen for Multi-Year RPPR The PDF version of the RPPR opens in a separate window. NOTE: The submitted RPPR can also be accessed from the RPPR Menu screen. The View RPPR as PDF option under the three-dot menu opens the PDF version of the RPPR. 5.11 Public Access Progress Report Additional Materials (PRAM) The Public Access Progress Report Additional Materials (PRAM) feature provides a means for the recipient to enter, review, and submit information in response to the automated notification sent when an NIH or AHRQ recipient organization submits an RPPR with non-compliant publications. The system sends the automated email to the PD/PI requesting verification that all publications are in compliance with the NIH Public Access Policy. The SO and AO assigned to the RPPR on the cover page (see Section A – Cover Page) will receive a copy (cc:) of the email. While an email response to the GMS and PO is acceptable at this time, the recipient is encouraged to respond using the Public Access PRAM feature in eRA Commons. Using the PRAM feature, recipients can upload and submit a My NCBI PDF report demonstrating that previously non-compliant papers reported on the RPPR are now compliant. Compliant papers have a status of Complete, N/A (not applicable), PMC Journal in Process, or In process at NIHMS. Please see http://publicaccess.nih.gov/include-pmcid-citations.htm for additional information. If unable to provide the verification of compliance, recipients can upload and submit justification for why specific publications cannot be brought into compliance. As with the RPPR, a PD/PI (or Contact PI in the case of multiple PIs) can enter the Public Access PRAM, but can only submit it if the PD/PI is delegated with Submit Progress Report authority. NIH RPPR Instruction Guide 59 January 2026 Otherwise, only the SO can submit the PRAM to Agency. The following sections cover the steps for initiating and submitting Public Access PRAM. 5.11.1 Initiate Public Access PRAM The PD/PI (Contact PI) or PD/PI Delegate can initiate Public Access PRAM by following the steps below: 1. Access the eRA Commons Status Result – List of Applications/Awards screen. 2. Select the Public Access PRAM link from the Available Actions column of the appropriate grant. The Progress Report Additional Materials (PRAM) screen displays. Grant Information including PD/PI Name, Project Title, Org Name (organization name), Status, and Current Reviewer displays at the top of the screen. The Public Access Compliance section at the bottom contains guidance for responding to the automated email requesting evidence of compliance, and also includes a “Drop files here..” area with a browse link. 3. Add the My NCBI PDF or another document providing justification by doing the following: Drag and drop the file(s) in the "Drop Files Here..." area, or click the browse link and choose file(s) from your drive. The drop files area specifies how many files and what file types are allowed. For uploaded files, you can: • Click the Download icon and the browser will open or download the file. • Click the Delete icon to remove the file. 3. Select the Route button at the bottom of the screen. Figure 55 Public Access PRAM Link NIH RPPR Instruction Guide 60 January 2026 Figure 56 Routing the Public Access PRAM When the Route button is selected, the Route PRAM to Next Reviewer screen displays. A list of all available reviewers exists in the drop-down for Next Reviewer. 4. Select an SO from the Next Reviewer drop-down list. 5. Enter text into the Comments field as necessary. This is not a mandatory field. 6. Select the Submit button to continue. Figure 57 Route Public Access PRAM to Next Reviewer NIH RPPR Instruction Guide 61 January 2026 The Route PRAM to Next Reviewer screen displays the PD/PI Assurance statement. 7. Read the assurance statement and select the Submit button to agree to the content and continue routing the PRAM to the next reviewer. The Progress Report Additional Materials (PRAM) screen displays with a message indicating that the PRAM was successfully routed to the selected reviewer. Additionally, the status is updated and shown as Reviewer Work in Progress. At this point, the PD/PI can only view the PRAM and may not edit it. To allow the PD/PI to edit the PRAM, the SO needs to route the PRAM back to the PD/PI using steps similar to those above. At the time of routing, an email is sent to the PD/PI and the selected SO (or other Next Reviewer) to notify them of the event. 5.11.2 Recall Public Access PRAM Public Access PRAM that has been routed to a reviewer can be recalled by the person who performed the routing action until the PRAM has been submitted to the Agency. This is useful in situations when the report was routed to the wrong person or the reviewer is unavailable. The last reviewer of the report is able to recall it; however, Signing Officials at the Organization and the Contact PD/PI who are not the last reviewer can also recall the report when it is in a status of Reviewer Work in Progress. NOTE: A PD/PI delegate does not have the ability to recall the PRAM. To recall Public Access PRAM, select the Recall button from the Progress Report Additional Materials (PRAM) screen. Figure 58 Public Access PRAM PD/PI Assurance Statement NIH RPPR Instruction Guide 62 January 2026 Figure 59 Recall Button for Public Access PRAM A message displays on the screen indicating: The PRAM has been successfully recalled. You have been set as the Current PRAM Reviewer. The status of the PRAM is updated to PD/PI Work in Progress if recalled by the PI or Reviewer Work in Progress if recalled by the SO; the reviewer from whom the PRAM is recalled receives an email about the action; and the PRAM routing audit history is updated to reflect the action. Additionally, the ability to remove uploaded files is restored and the Route button is enabled, providing the current reviewer the ability to update the PRAM and route it again. 5.11.3 Submit Public Access PRAM When the Public Access PRAM is in Reviewer Work in Progress status, the Signing Official (SO) can submit it to the Agency. PD/PIs may also submit the information if they have been delegated Submit Progress Report authority by the SO. To submit the Public Access PRAM: 1. Access the Status screen on eRA Commons. 2. Enter the appropriate query parameters to locate the award and select the Search button. The Status Result – General Search screen displays with the matching information. 3. From the three-dot ellipsis menu, select the link for Public Access PRAM. NIH RPPR Instruction Guide 63 January 2026 Figure 60 Public Access PRAM Link for SO The Progress Report Additional Materials (PRAM) screen displays. The screen displays Grant Information on top and the PD/PI comments in the text box at the bottom of the screen. In addition to submitting the PRAM, from this screen, the SO also may Preview the PRAM as a PDF, Route it to another reviewer (or back to the PD/PI), and view the Routing History. Select any of the appropriate buttons to perform these actions. Follow the steps below to continue submitting the PRAM. 4. Click the Submit button. Figure 61 Submitting Public Access PRAM NIH RPPR Instruction Guide 64 January 2026 The Submit PRAM to Agency screen displays. By continuing from this screen, the SO certifies that the submitting organization is in compliance with the terms and conditions specified in the Notice of Award and Grants Policy Statement. The SO also verifies that the information provided in the PRAM is valid and accurate. 5. Read certification agreement. Select the I Agree button to continue submitting the information. (Selecting the Cancel button closes the screen and returns to the Progress Report Additional Materials screen without submitting the material.) The Progress Report Additional Materials (PRAM) screen displays with a message indicating that the PRAM was successfully submitted. The current reviewer is updated to ‘Agency’, the PRAM status is updated to Submitted, and the PRAM submission date is recorded. The routing history is updated to reflect the submission to the Agency. Figure 62 SO Certification of Public Access PRAM NIH RPPR Instruction Guide 65 January 2026 Figure 63 Public Access PRAM Submitted to Agency When PRAM is submitted to Agency, an email notification is sent to the PD/PI (Contact PI) on the award, the submitting SO, the SO assigned to the RPPR, Interim-RPPR, or Final RPPR and AO assigned to the RPPR. NOTE: To view the submitted PRAM, click the Public Access PRAM link on the application/award again, and click the Preview button on the Progress Report Additional Materials (PRAM) screen. This option opens the PRAM PDF in a separate window. The Public Access PRAM will appear as the final page of the PDF document. See below for another way to display Public Access PRAM. 5.11.4 View Public Access PRAM for Multi-Year Funded Awards After submitting Public Access PRAM for multi-year funded awards, users with access to the award information may view the PRAM via the Status Information screen. Status Information is accessed by selecting the Application/Award ID link from the Status Result – General Search (SOs) and Status Result – List of Applications/Awards (PIs) screens. NIH RPPR Instruction Guide 66 January 2026 Figure 64 Status Results Showing link for Application/Award ID From the Status Information screen, select the hyperlink in the area marked Progress Report Additional Material (PRAM) in the Other Relevant Documents section. The PRAM links for multi- year funded awards display as PRAM Year <X> <date submitted>. Figure 65 MYF Award PRAM Link in Status Information NIH RPPR Instruction Guide 67 January 2026 5.12 Final Progress Report Additional Materials (FRAM) A Final Research Performance Progress Report (Final RPPR) is required for any award that has ended and any award that is not to be extended through award of a new competitive segment. This report should be prepared in accordance with instructions provided by the awarding component. The Final Progress Report Additional Materials (FRAM) feature provides a means for recipients to enter, review, route, and submit information in response to specific request(s) by the Program Official (PO) for additional information related to the Final RPPR. While reviewing a submitted Final RPPR, the PO may determine that additional materials related to the submitted report are required. In this case, the PO will submit a request for this information referred to as a FRAM request. When a FRAM request is made, the PI is notified via email; Final RPPR status on Closeout Status is updated to FRAM Requested; and a FRAM Update link appears in the Closeout Status screen. The link is located as an action on the FRAM line for Closeout Submission Requirement. This section discusses th